Most American don't know that in 1986, Congress passed a law that gave pharmaceutical companies complete immunity from liability for injuries caused by vaccines. Shingrix is the preferred vaccine because it has been shown to be more effective. 5 inches, she added. But suppose you haven’t been vaccinated and you get shingles for the first time. Therefore, people worried about spreading the disease to the people around them. SHINGRIX is a vaccine indicated for prevention of herpes zoster (HZ) (shingles): in adults aged 50 years and older. By 2026, GSK plans to double that figure. Message. The live zoster vaccine (LZV, Zostavax ®) was the first proof of concept that vaccination could prevent HZ, but LZV cannot be used in various immune-compromised patients. Shingrix® will be able to be ordered online via the ImmForm website for those who are eligible for shingles vaccination but are clinically contraindicated to receive the live vaccine Zostavax. There have been reports of people getting ill from GBS days or weeks after being vaccinated with Shingrix, the shingles vaccine, and after getting the flu shot. The FDA and CDC recommend that adults ages 50 years and older have the Shingrix vaccine. C. To date, there is no authorized importation nor distribution yet of the said vaccine. The vaccine is given in two doses with two to six months. 1, 2021, in the Journal of the American Academy. This led to the development of a new non-live recombinant zoster vaccine (RZV, Shingrix ®). It is Schedule 4 : Prescription Only Medicine. My head ached constantly, and my stomach hurt after eating. The Shingrix vaccine was approved for use in adults 50 years of age or over in the US, Canada and Australia in 2017, and for use in the European Union and Japan in 2018. is formally bidding adieu to more than 1,000 lawsuits alleging its shingles vaccine Zostavax caused patients to develop the. Limitations of Use: •. It helps prevent shingles (herpes zoster). However, key differences in the immune responses elicited by VZV. , provides seven to 10 years of protection following the initial two-dose administration, according to infectious disease experts. As of August 2, 2023, I am still not feeling well. This includes any vaccine that is normally recommended for those 50 years and older, such as the pneumococcal and influenza vaccines. 0ºF to 46. 4. Reference: 1. 51%, respectively). The most common side effects of either shingles vaccine are redness. Although a person can still develop shingles once vaccinated, since the vaccine is not 100% effective, a person cannot get shingles from the Shingrix vaccine. 1,2 The vaccine can be given to patients with cancer even if they are receiving or have recently. In a complaint filed in a Conn…The warning is the second that the agency has issued for the Johnson & Johnson vaccine: In April, it warned of an increased risk of blood clots coupled with low platelets, components of blood that. stomach pain. The key injury, incredibly, is that the Zostavax shingles vaccine causes shingles and zoster-related injuries. Claims, so far mostly filed in state and federal courts in Pennsylvania, cover injuries ranging from rashes to. Shingrix® will replace Zostavax® for the whole shingles programme; Shingrix® will require a 2-dose schedule for all cohorts. In a complaint filed in a. Studies show that Shingrix is 98 percent effective against shingles for people between the ages of 50 and 69, and 91 percent effective against post-herpetic neuralgia for people 50 and. The pain from shingles has been compared to childbirth or passing a kidney stone. Shingrix is the preferred vaccine for use in people who are immunocompromised. In adults with weakened immune systems, the vaccine was 68%-91%. Shingrix® vaccine for people with weakened immune systems. Shingrix is an FDA-approved vaccine to help prevent the occurrence of herpes zoster (shingles). Global health care giant GlaxoSmithKline LLC (GSK) agreed to plead guilty and to pay $3 billion to resolve its criminal and civil liability arising from the company’s unlawful promotion of certain prescription drugs, its failure to report certain safety data, and its civil liability for alleged false price reporting practices, the Justice Department announced today. Shingrix is a recombinant zoster vaccine that has been available since 2017 and is. How much you pay will vary based on the plan you choose. In terms of effectiveness, Foster says the probable reason. Shingrix is a non-live recombinant vaccine approved by the Food and Drug Administration (FDA) in 2017 to prevent shingles and postherpetic neuralgia in immunocompetent adults age 50 years and older. The immuneEighteen patients filed a lawsuit against Merck, claiming its shingles vaccine Zostavax caused them to contract shingles and, in two cases, to develop persistent nerve pain related to the virus. TTS, CDC researchers told the panel Thursday, was seen once in 250,000 recipients of the J&J vaccine, but was more common among women in their 30s and 40s, where it occurred once in 100,000. Shingrix is an inactivated vaccine that has been used since 2017. You can get Shingrix at your healthcare provider's office or pharmacy. While its cause is not fully understood, the syndrome often follows infection with a virus or bacteria. Shingles vaccine can help prevent shingles and the complications from the disease. S. Click on a tab below…. 1The ZOE-50 trial (NCT01165177) assessed the efficacy of recombinant zoster vaccine compared with a. adults aged ≥50 years. March 8, 2023. Instead of the whole, weak virus in Zostavax, Shingrix uses only a piece of the varicella-zoster virus. A couple of days later I started feeling extremely light headed and started running fever of 100. The National Psoriasis Foundation advises people over age 50 with. Details on ImmForm vaccine coverage data collection are set out below. In a. Acute Immune Thrombocytopenia following administration of Shingrix recombinant zoster vaccine. Learn More About this Lawsuit SEE IF YOU QUALIFY FOR. Difficulty breathing. Shingrix is a nonliving vaccine made of a virus component. The Shingrix vaccine can prevent shingles and lessen the intensity of symptoms if you have the condition. that is currently undergoing evaluation for its monitored release registration application. Shingles vaccine can help prevent shingles and the complications from the disease. People who are age 19 or older and are taking certain MS medications should receive a Shingrix vaccine. Zostavax Shingles Vaccine Lawsuits. zoster, live) vaccine’ with ‘Zostavax®’ • reflect recommendations in the revised Green Book Chapter 28a and changes to the national shingles programme following the introduction of Shingrix® vaccine (see PHE Shingrix PGD) with amendment to the criteria for exclusion, cautions, actions if excluded, drug interaction and additionalHow is the shingles vaccine made? The shingles vaccine available in the U. Zostavax is a vaccine that's supposed to prevent shingles, but instead, it may actually cause shingles, vision problems, hearing problems, stroke. Individuals who are severely immunocompromised aged 50 years and over. The vaccine prevents more than 90% of cases of shingles in adults 50 years and older. Since October 2022, provincial PharmaCare for low-income people has covered the $11. The FDA approved the Shingrix vaccine in October 2017 for adults age 50 and older after it was found to reduce the risk of herpes zoster by 97. a high temperature. Shingrix is set to replace Zostavax as the primary defender against shingles. 5 mL. The key injury, incredibly, is that the Zostavax shingles vaccine causes shingles and zoster-related injuries. If you have had chickenpox in the past, you may get shingles later in life. The lawsuit alleges that Merck’s defective Zostavax vaccine was the direct cause of Mr. From 1 September 2021, people who are 70 to 79 years of age with weakened immune systems will be offered the. According to CDC, it is safe. For those who still get shingles after being immunized, the vaccine. 5% of those that turned 70 and 25. GlaxoSmithKline recently closed out a voluntary recall of 130,500 doses of its market-leading shingles vaccine Shingrix after finding cracks in two vials. During the first eight months of Shingrix’s post-marketing use, the Vaccine Adverse Event Reporting System, or VAERS, received 4,381 total reports of adverse events; of these 130 were serious. Shingrix is the preferred vaccine for use in people who are immunocompromised. The challenge facing Pfizer will be two fold: (1) Shingrix is 97-99% effective across 2 years in older adults with no age-related lack of efficacy. The shingles vaccine Shingrix may also increase the risk of the condition. The safety and efficacy of Shingrix in children and adolescents have not been established. Geriatrics; Infectious Disease; Primary Care;Vaccine-related reactions are common in patients receiving Shingrix with 78% of patients reporting some injection site pain. Epub 2021 Mar 11. The most common side effects of a shingles vaccine are redness, pain, tenderness, swelling and itching at the injection site, and headaches. In phase 3, the two-dose Shingrix showed that it is 97. Merck & Co. October 27, 2017 — Immunization experts have voted in favor of updating guidelines to recommend Shingrix® over an older shingles vaccine called Zostavax®. However, it can be stored in the refrigerator and used up to 6 hours after reconstitution. Shingrix, which has already been approved for use in the European Union, the United States, Canada, Japan and Australia, brought in 357 million pounds ($452. shivering. I had a pneumonia vaccine the same day. Took the Shingrix vaccine on 7-12-23 and woke up with fever, body aches, dizziness and fatigue. It helps prevent shingles (herpes zoster). Authors. 5 ml each), 2 to 6 months apart (0, 2-6 months). The CDC recommends vaccination for adults age 50 and over, or any adult who is immunocompromised. Details on ImmForm vaccine coverage data collection are set out below. It requires two doses, administered 2-6 months apart. NOTE: Reconstituted vaccine should never be placed in the freezer. So the very thing meant to protect them against shingles caused shingles. , et al. Better to download the form, fill it out, and then submit it. The vaccine uses a live, weakened form of the chickenpox and shingles virus. You had a severe (serious) or unusual side effect after this vaccine or one like it. Shingrix is an inactivated vaccine that has been used since 2017. The shingles vaccine Shingrix has replaced Zostavax on the NIP. New Warning about Risk for GBS following Shingrix. Shingrix is recommended as the preferred vaccine by the Advisory Committee on Immunization Practices, a group of medical and public health experts. Experts recommend that people over 50 get this vaccine. People can receive Shingrix in two doses, with a separation of 2–6 months between shots. S. It combines an antigen, glycoprotein E, and an adjuvant system, AS01B, intended to generate a strong and long-lasting immune response that can help overcome the decline in. The number of doses: Zostavax is a one-shot vaccine. The addition of Shingrix® to the NIP and PBS would enable better access to the most suitable vaccine (ie the inactivated varicella zoster vaccine) to prevent varicella zoster in this vulnerable patient group. C. Individuals should get their second Shingrix dose 2 to 6 months after their first dose. A live-attenuated zoster vaccine (LZV) first authorized in 2008 was discontinued in 2023. Like most vaccinations, the vaccine will be given as an injection in your upper arm. ages 18 years and older who have an increased risk of. The second vaccine, Shingrix®, has been available since 2017. Who is eligible to receive the publicly funded Shingrix ® vaccine?Shingrix can be given with the same schedule in individuals previously vaccinated with live attenuated HZ vaccine (see section 5. You can get Shingrix at your healthcare provider's office or pharmacy. by Kendall Heebink. It will be available for eligible people most at risk of complications from shingles. The shingles shot side effects are usually mild and go away within a few days. shivering (chills) More serious side effects such as a severe allergic reaction are very rare. Vaccine Injury Clinic, George Washington Univ. Receiving the shingles vaccine lowered the risk of stroke by about 16%, lowered the risk of ischemic (clot-caused) stroke by about 18% and lowered the risk of hemorrhagic (bleeding) stroke by about 12%; The vaccine’s protection was strongest among people ages 66 to 79 years; and. If SHINGRIX is given at the same time as the influenza vaccine, a different injection site will be used for each vaccine. 1. Get a Free Zostavax Shingles Vaccine Lawsuit Evaluation With Our Lawyers. swollen, painful, or tender lymph glands in the neck, armpit, or groin. Despite earning Merck as much as $685 Million a year, the vaccine's sales quickly dropped after the U. The Herpes Zoster virus is. Shingrix ® is a recombinant subunit, adjuvanted vaccine indicated for prevention of Herpes Zoster (shingles)and is provided as a 2-dose immunization series. The Shingrix vaccine is also recommended for anyone who has already gotten another type of shingles vaccine. Common Shingrix side effects include: headache, muscle pain; feeling tired; stomach pain, nausea, vomiting, diarrhea; fever, shivering; or. You should tell patients to expect such reactions as pain, swelling, and redness. A new shingles vaccine, Shingrix, or herpes zoster subunit (HZ/su) vaccine, was approved by the Food and Drug Administration in 2017 and was demonstrated in clinical trials to have an overall efficacy of over 95% in patients aged 50 or older. Shingrix (recombinant zoster vaccine) should be. Hence, proper counseling and education about the risks of herpes should be informed to the patients with timely utilization of the vaccine. Shingrix is safe for people with psoriasis and psoriatic arthritis. Is there a free shingles vaccine for seniors? Beginning Jan. The list price for for a single dose of Shingrix is $183. Vaccination is a safe and effective way to protect you from serious disease caused by shingles (herpes zoster) The risk of getting shingles and neurological complications increases with age. Most people are eligible to get the shingles vaccine starting at age 50. 0ºC). Shingles vaccine. an aching body. Roughly 3-4 weeks later my left eye was (seemed like over-night) puffy, black and. Further detailed information and guidance for healthcare professionals relating to this . A live-attenuated zoster vaccine (LZV) first authorized in 2008 was discontinued in 2023. 5 mL each), 2 to 6 months apart. Almost 6,000 participants were enrolled in the trial, which was. Shingrix is more than 90% effective at preventing shingles and postherpetic neuralgia. The Shingrix vaccine (whose two doses are to be given two to six months apart), according to the CDC, offers 97 percent protection in people in their 50s and 60s and roughly 91 percent protection. ages 18 years and older who have an increased risk of. D. 2016 Jul;155 (1):81-6. muscle aches. 8% in participants aged 70 years or older when compared with placebo. Julie Steinberg. 127 Comments. CDC Warns Of Errors In Giving Shingrix Shingles Vaccines. What do we know about its connection to the Covid-19 vaccines? Of the 100 reports of the syndrome after vaccination, 95. The most common side effects of a shingles vaccine are redness, pain,. 1, 2023, Medicare covers the entire cost of Shingrix. SHINGRIX can be given at the same time as the yearly influenza (flu) vaccine. Learn about the zoster (shingles) vaccine, its benefits and risks, and who should get it. Center of Disease Control recommended in 2017 that adults ask for Shingrix instead of. Second dose I got a rash on and around the injection site. Efficacy of a single dose and a delayed second. Monobasic sodium phosphate dihydrate. Monophosphoryl lipid A is a detoxified form. CDC recommends Shingrix (recombinant zoster vaccine, or RZV) for the prevention of herpes zoster (shingles) and related complications. 1, 2023, Medicare covers the entire cost of Shingrix. Clinical Considerations for Use of Recombinant Zoster Vaccine (RZV, Shingrix) in Immunocompromised Adults. Shingrix Dosage and Schedule. In GSK’s first quarter after the Haleon consumer health spinoff, shingles vaccine Shingrix put up. Patients allege developing headaches, dizziness and blurred vision. Shingrix is not an mRNA vaccine like the. I developed a fever, blinding headache, shaking chills, weakness, joint & muscle pain. It’s given in two doses, with two to six months between doses. Shingrix is the vaccine approved by the Food and Drug Administration in 2017 to help prevent shingles in older adults. Some vaccines may be affected by other vaccines. It is important to discuss this vaccine with your MS healthcare. Shingrix is used for adults age 50 years and older and for adults age 18 years and older with a weakened immune system who are at risk of herpes zoster infection. SHINGRIX can be given at the same time as the yearly influenza (flu) vaccine. The company's shingles shot Shingrix generated nearly £2 billion (around $2. The Food and Drug Administration (FDA) has approved it to prevent shingles (herpes zoster) in people: ages 50 years and older. Post-Donut Hole. FREE – $212. GSK’s Shingrix (Recombinant Zoster Vaccine or RZV) vaccine has been shown to offer 100 percent efficacy against shingles in adults 50 years old and over in China. loss of bladder or bowel control. CDC researchers said that the Shingrix success rate was above 90%, which, combined with the total number of adverse events, puts Shingrix in line with most vaccines, meaning it is overwhelmingly safe. At the time of vaccination, the mean age of the population was 69 years;The vaccines should be administered at different injection sites. If you or somebody you know had a shoulder injury, you should contact our lawyers immediately for a free case consultation. Shingrix® (non-live recombinant Herpes Zoster vaccine) Shingrix® is recommended for adult SOT by transplant physicians for those 18 years of age and older. The National Vaccine Injury Compensation Program is a no-fault alternative to the traditional legal system for resolving vaccine injury petitions. Since most of us have had chickenpox in the past, the shingles vaccine is an easy way to prevent the dormant chickenpox virus from creeping up and hitting you again with shingles. These side effects may affect your ability to do daily activities, but they should go away on their own in a few days. I spent three days in bed and had low grade fever on and off for two weeks. The dosing interval will differ for. The damage to the nerves causes muscle weakness and sometimes paralysis. In a cohort analysis, they compared 849,397 people vaccinated with RZV and 1,817,099 people who had zoster vaccine live (ZVL; Zostavax) from October 2017 through December 2018 For Herpes Zoster, Prophylaxis "I am a 64 year old female in excellent health who received the 1st shot of the Shingrix vaccine on 10/6/20. In one late-stage trial, 9 of 7,340 people given Shingrix developed shingles, compared with 254 of 7,413 participants who received a placebo. S. It's called Zostavax® and is a live, weakened form of the chickenpox (varicella) virus. Zostavax reduced the risk of shingles by 51% and the risk of post-herpetic neuralgia by 67% in a study of more than 38,000 adults aged 60 years or older. After several plaintiffs filed lawsuits claiming the drugmaker’s shingles vaccine caused serious injury and death, attorneys say more cases are on the way. Who needs the shingles vaccine? The CDC recommends all adults age 50 and older, get. Shingrix Guillain-Barré Syndrome Risk Seen During 42 Days After Shingles Vaccination: Study. Food and Drug Administration last year. Shingrix is recommended to prevent shingles and related complications in immunocompetent adults 50 years and older, and for adults 19 years and older who are or will be immunocompromised. The CDC recommends that all healthy adults. November 20th 2023. fever. Didnt work. Pharmaceutical giant GlaxoSmithKline (GSK) has recently launched a new vaccine Shingrix in India to protect against shingles, a painful skin condition caused by the varicella-zoster virus. Doses are given two to six months apart. Shingles is the adult version of chickenpox and it most often affects people over the age of 50. It works by boosting the immune system of people who once had chickenpox. However, if the side. RZV is recommended for individuals ≥50 years of age without contraindications. Zostavax, the shingles vaccine used previously and now discontinued, wasn’t as effective as Shingrix. 0ºF to +5. Shingrix, a shingles vaccine in the U. When this happens, the infection is usually much milder compared with infection caused by the virus the vaccine protects against. The vaccine prevents more than 90% of cases of shingles in adults 50 years and older. If there's one problem with. Details. Among more than 1. 161004102. It has been used since October 2017. Shingrix is preferred by FDA which is a two doses vaccine that is given 6 months apart for people above 50 years and to immunocompromised people. If you or somebody you know was diagnosed with Guillain-Barré Syndrome, you should contact our lawyers immediately for a free case consultation. The vaccine is more than 90% effective at keeping you from getting shingles and its related complications, which can include. The complaint accused Merck of failing to exercise care in designing, labeling and distributing the vaccine. Shingles can cause severe pain that can last for. Among the. Since Shingrix uses only a piece of the varicella-zoster virus to train the immune system, the vaccine can't cause illness in anyone else. 05 billion) for the exclusive rights to distribute GSK's shingles vaccine in the world's No. You can have the vaccine even if you previously had the Zostavax shot. The adverse reactions of fever and shivering were more frequent when PPV23 vaccine is co-administered with Shingrix. Live vaccines contain a live, weakened version of the germ they protect against. 20201 Toll Free Call Center: 1-877-696-6775 . [7]Shingrix is an effective vaccine that can protect you against shingles outbreaks and complications like post-herpetic neuralgia. As the frontline system for. The shingles vaccine, Shingrix. Shingrix® is a. Shingles is a painful, blistering rash caused by the. Development of the therapeutic Shingrix vaccine for Herpes Zoster and a prophylactic vaccine for varicella zoster virus (VZV) has increased efforts for HSV vaccine due to similarities between the two viruses, especially with the establishment of latency (Heineman et al. Ankle, knee, or great toe joint pain. According to the manufacturer, 95% of privately insured people can get the shingles vaccine for free. The vaccine is highly effective in more than 95% of recipients up to the age of 70. 2021 May 1;96(5):E136-E137. The CDC recommends adults 50 years and older get two doses of the shingles vaccine called Shingrix to prevent complications from the disease. A February 2019 study reported that about 24 percent of people who had Shingrix. Guillain-Barré syndrome (GBS) is a rare disorder where the body’s immune system damages nerve. Manufacturers made large payouts to individuals and families claiming vaccine injury, particularly from the combined diphtheria-pertussis-tetanus (DPT) immunization. com. W. Injection site was swollen like and egg and hurt for days. The vaccines should be administered at different injection sites. This joint letter from Public Health England and NHS England and NHS Improvement sets out the details of the introduction of the Shingrix® vaccine for immunocompromised individuals from. The shingles vaccine is the best way to protect you from getting shingles. Zostavax Lawsuit. II (Merck Canada Inc. How much does the shingles vaccine cost? As of January 2023, manufacturer GSK reports the list price for the Shingrix vaccine as. This RZV has shown promising results in many clinical trials, with high. That rash spread to my chest, back, arms, buttocks, lower legs. Side effects can last two or three days, and the injection site in the upper arm can hurt. Both Shingrix and Zostavax shingles vaccines have been shown to be safe and well tolerated. 5cm apart. Federal health experts are warning about the risk of problems with Shingrix, GlaxoSmithKline’s shingles vaccine, indicating that errors have been reported in recent months due to. Dosage and Administration: Shingrix is administered by intramuscular injection in two doses of 0. That I fought for over a month. The Zostavax vaccine is an exception. Merck & Co. could be facing an increasing number of lawsuits alleging its shingles vaccine Zostavax has caused injury and death, reports The Legal Intelligencer, citing attorneys involved in legal action against the pharma company. SHINGRIX is a product of GlaxoSmithKline Philippines (GSK) Inc. Shingrix is the U. Once the dominant shingles vaccine on the market, Zostavax was eclipsed by Shingrix shortly after its launch by GlaxoSmithKline in 2017. According to Shingrix's FDA label, 78% of vaccine recipients experienced pain at the injection site in clinical tests. Symptoms of an allergic reaction (called anaphylaxis) include: Hives. If either is observed, do not reconstitute the vaccine. Zostavax is a live vaccine that has been used since 2006. Stuart Bradford. The deal is one of a series of moves by western pharmaceutical firms to seize a bigger share of China's market, including. GSK voluntary recall Shingrix FDA. Hundreds of lawsuits are pending against the maker of Zostavax after people claimed they suffered adverse reactions when. Administering and storing Shingrix. blindness. S. You have shingles or had shingles in the last year. Shingrix is a nonliving vaccine made of a virus component. S. Attention Lawyers: We consider a referral from another law firm to be. A federal judge has dismissed more than 1,100 Zostavax lawsuits claiming the vaccine caused recipients to develop shingles, which it was supposed to prevent. 9% experienced swelling. Please use the form below to contact our Vaccine Injury Litigation Group or call us toll-free 24 hours a day at (866) 920-0753. The Shingrix vaccine is more than 90% effective at helping you prevent shingles. 5-101. RZV is recommended for individuals ≥50 years of age without contraindications. 5 ml each), 2 to 6 months apart (0, 2-6 months). Skin rash, joint pain, flu-like symptoms, headaches and fatigue are some complaints from patients who've had the recently approved Shingrix vaccine. In our case report, we describe for the first time an alleged temporal relationship between the administration of Pneumovax and Shingrix vaccines and the development of ASS. Shingles is a painful rash illness, which sometimes leads to long-term nerve pain. recombinant zoster vaccine (RZV or SHINGRIX) to immunocompetent adults aged 50 years and older. For immunocompromised adults, a shorter interval of 1. Who can get the free vaccine? A 2-dose course of Shingrix ® will be available free for: • people aged 65 years and over • Aboriginal and Torres Strait Islander people aged 50 years and over, andShingrix was approved by the U. The vaccine aims to prevent shingles (herpes zoster) and post-herpetic neuralgia in adults aged 50 years and above. The CDC-recommended vaccine, Shingrix, is a recombinant zoster vaccine that has two doses administered within six months of each other. 5. There are no other known drug interactions with Shingrix® vaccines. Shingrix is a recombinant vaccine that prevents shingles and related complications in older and immunocompromised adults. Shingles Vaccine Lawsuits. Please use the form below to contact our Vaccine Injury Litigation Group or call us toll-free 24 hours a day at (866) 920-0753. Shingrix is a type of recombinant vaccine. joint stiffness or swelling. The Shingrix vaccine contains a weakened version of the VZV. 2019. In addition, the company did not provide. The CDC. Looking at VICP claims in that time period, the most common vaccines involved in an alleged injury that led to compensation were influenza (1188), Tdap (141), and DTaP (113). This means. The shingles vaccine does not contain thimerosal (a preservative containing. Changes to the shingles vaccine available under the National Immunisation Program (NIP) came into effect from 1 November 2023. Shingrix is a subunit vaccine consisting of a recombinant VZV envelope glycoprotein E antigen lyophilized component that is reconstituted at the time of use with AS01 B. Protection stays strong for at least four years after you get vaccinated. 1,4 This includes individuals who have received Zostavax ® prior to transplant. There is no live virus in recombinant shingles vaccine. Federal health experts are warning about the risk of problems with Shingrix, GlaxoSmithKline’s shingles vaccine, indicating that errors. 5.